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Dna2 processes behind the fork long ssDNA flaps generated by Pif1 and replication-dependent strand displacement
Dna2 is a DNA helicase-endonuclease mediating DSB resection and Okazaki fragment processing. Dna2 ablation is lethal and rescued by inactivation of Pif1, a helicase assisting Okazaki fragment maturation, Pol32, a DNA polymerase δ subunit, and Rad9, a DNA damage response (DDR) factor. Dna2 counteract...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240037/ https://www.ncbi.nlm.nih.gov/pubmed/30446656 http://dx.doi.org/10.1038/s41467-018-07378-5 |