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NUAK2 is a critical YAP target in liver cancer

The Hippo-YAP signaling pathway is a critical regulator of proliferation, apoptosis, and cell fate. The main downstream effector of this pathway, YAP, has been shown to be misregulated in human cancer and has emerged as an attractive target for therapeutics. A significant insufficiency in our unders...

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Detalles Bibliográficos
Autores principales: Yuan, Wei-Chien, Pepe-Mooney, Brian, Galli, Giorgio G., Dill, Michael T., Huang, Hai-Tsang, Hao, Mingfeng, Wang, Yumeng, Liang, Han, Calogero, Raffaele A., Camargo, Fernando D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240092/
https://www.ncbi.nlm.nih.gov/pubmed/30446657
http://dx.doi.org/10.1038/s41467-018-07394-5