A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival

Common disorders, including diabetes and Parkinson’s disease, are caused by a combination of environmental factors and genetic susceptibility. However, defining the mechanisms underlying gene-environment interactions has been challenging due to the lack of a suitable experimental platform. Using pan...

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Detalles Bibliográficos
Autores principales: Zhou, Ting, Kim, Tae Wan, Chong, Chi Nok, Tan, Lei, Amin, Sadaf, Sadat Badieyan, Zohreh, Mukherjee, Suranjit, Ghazizadeh, Zaniar, Zeng, Hui, Guo, Min, Crespo, Miguel, Zhang, Tuo, Kenyon, Reyn, Robinson, Christopher L., Apostolou, Effie, Wang, Hui, Xiang, Jenny Zhaoying, Evans, Todd, Studer, Lorenz, Chen, Shuibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240096/
https://www.ncbi.nlm.nih.gov/pubmed/30446643
http://dx.doi.org/10.1038/s41467-018-07201-1

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