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Footprints of antigen processing boost MHC class II natural ligand predictions

BACKGROUND: Major histocompatibility complex class II (MHC-II) molecules present peptide fragments to T cells for immune recognition. Current predictors for peptide to MHC-II binding are trained on binding affinity data, generated in vitro and therefore lacking information about antigen processing....

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Detalles Bibliográficos
Autores principales:	Barra, Carolina, Alvarez, Bruno, Paul, Sinu, Sette, Alessandro, Peters, Bjoern, Andreatta, Massimo, Buus, Søren, Nielsen, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240193/ https://www.ncbi.nlm.nih.gov/pubmed/30446001 http://dx.doi.org/10.1186/s13073-018-0594-6

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