High expression of Tob1 indicates poor survival outcome and promotes tumour progression via a Wnt positive feedback loop in colon cancer

Tob1, a Tob/BTG anti-proliferative protein family member, functions as a tumour suppressor in many cancers. Here, we reveal a unique oncogenic role of Tob1 in colon cancer. Tob1 expression was upregulated during colon cancer progression, was significantly correlated with tumour size and tumour diffe...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Xiao, Li, Ge, Yuetan, Fu, Yu, Zhang, Wenqing, Cao, Hanwei, Chen, Binbin, Wang, Haibin, Zhan, Yan-yan, Hu, Tianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240287/
https://www.ncbi.nlm.nih.gov/pubmed/30447686
http://dx.doi.org/10.1186/s12943-018-0907-9

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