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Mechanistic Insights into Colorectal Cancer Phenomics from Fundamental and Organotypic Model Studies

Colorectal cancer (CRC) diagnosis and prognostic stratification are based on histopathologic assessment of cell or nuclear pleomorphism, aberrant mitotic figures, altered glandular architecture, and other phenomic abnormalities. This complexity is driven by oncogenic perturbation of tightly coordina...

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Detalles Bibliográficos
Autores principales: Campbell, Frederick C., Loughrey, Maurice Bernard, McClements, Jane, Deevi, Ravi Kiran, Javadi, Arman, Rainey, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240511/
https://www.ncbi.nlm.nih.gov/pubmed/30028958
http://dx.doi.org/10.1016/j.ajpath.2018.05.021