Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of t...

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Detalles Bibliográficos
Autores principales: Ferry, Tristan, Leboucher, Gilles, Fevre, Cindy, Herry, Yannick, Conrad, Anne, Josse, Jérôme, Batailler, Cécile, Chidiac, Christian, Medina, Mathieu, Lustig, S, Laurent, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240628/
https://www.ncbi.nlm.nih.gov/pubmed/30474047
http://dx.doi.org/10.1093/ofid/ofy269
Descripción
Sumario:Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required.

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