Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?

Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of t...

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Autores principales: Ferry, Tristan, Leboucher, Gilles, Fevre, Cindy, Herry, Yannick, Conrad, Anne, Josse, Jérôme, Batailler, Cécile, Chidiac, Christian, Medina, Mathieu, Lustig, S, Laurent, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240628/
https://www.ncbi.nlm.nih.gov/pubmed/30474047
http://dx.doi.org/10.1093/ofid/ofy269
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author Ferry, Tristan
Leboucher, Gilles
Fevre, Cindy
Herry, Yannick
Conrad, Anne
Josse, Jérôme
Batailler, Cécile
Chidiac, Christian
Medina, Mathieu
Lustig, S
Laurent, Frédéric
author_facet Ferry, Tristan
Leboucher, Gilles
Fevre, Cindy
Herry, Yannick
Conrad, Anne
Josse, Jérôme
Batailler, Cécile
Chidiac, Christian
Medina, Mathieu
Lustig, S
Laurent, Frédéric
author_sort Ferry, Tristan
collection PubMed
description Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required.
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spelling pubmed-62406282018-11-23 Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection? Ferry, Tristan Leboucher, Gilles Fevre, Cindy Herry, Yannick Conrad, Anne Josse, Jérôme Batailler, Cécile Chidiac, Christian Medina, Mathieu Lustig, S Laurent, Frédéric Open Forum Infect Dis Brief Report Local injection of a bacteriophages mix during debridement, antibiotics and implant retention (“DAIR”) was performed to treat a relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment was safe and associated with a clinical success. Scientific evaluation of the potential clinical benefit of bacteriophages as antibiofilm treatment in PJI is now feasible and required. Oxford University Press 2018-10-24 /pmc/articles/PMC6240628/ /pubmed/30474047 http://dx.doi.org/10.1093/ofid/ofy269 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Ferry, Tristan
Leboucher, Gilles
Fevre, Cindy
Herry, Yannick
Conrad, Anne
Josse, Jérôme
Batailler, Cécile
Chidiac, Christian
Medina, Mathieu
Lustig, S
Laurent, Frédéric
Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title_full Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title_fullStr Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title_full_unstemmed Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title_short Salvage Debridement, Antibiotics and Implant Retention (“DAIR”) With Local Injection of a Selected Cocktail of Bacteriophages: Is It an Option for an Elderly Patient With Relapsing Staphylococcus aureus Prosthetic-Joint Infection?
title_sort salvage debridement, antibiotics and implant retention (“dair”) with local injection of a selected cocktail of bacteriophages: is it an option for an elderly patient with relapsing staphylococcus aureus prosthetic-joint infection?
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240628/
https://www.ncbi.nlm.nih.gov/pubmed/30474047
http://dx.doi.org/10.1093/ofid/ofy269
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