PINK1 Protects Against Gentamicin-Induced Sensory Hair Cell Damage: Possible Relation to Induction of Autophagy and Inhibition of p53 Signal Pathway

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1) is a gatekeeper of mitochondrial quality control. The present study was aimed to examine whether PINK1 possesses a protective function against gentamicin (GM)-induced sensory hair cell (HC) damage in vitro. The formation of park...

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Detalles Bibliográficos
Autores principales: Yang, Qianqian, Zhou, Yiwei, Yin, Haiyan, Li, Hongrui, Zhou, Meijuan, Sun, Gaoying, Cao, Zhixin, Man, Rongjun, Wang, Haibo, Li, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240688/
https://www.ncbi.nlm.nih.gov/pubmed/30483050
http://dx.doi.org/10.3389/fnmol.2018.00403

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