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Carbohydrate Targets for CAR T Cells in Solid Childhood Cancers

Application of the CAR targeting strategy in solid tumors is challenged by the need for adequate target antigens. As a consequence of their tissue origin, embryonal cancers can aberrantly express membrane-anchored gangliosides. These are carbohydrate molecules consisting of a glycosphingolipid linke...

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Detalles Bibliográficos
Autores principales:	Rossig, Claudia, Kailayangiri, Sareetha, Jamitzky, Silke, Altvater, Bianca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240699/ https://www.ncbi.nlm.nih.gov/pubmed/30483473 http://dx.doi.org/10.3389/fonc.2018.00513

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