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FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases characterized by the progressive loss of specific groups of neurons. Due to clinical, genetic and pathological overlap, both diseases are considered as the extremes of one disease spectrum and in a n...

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Detalles Bibliográficos
Autores principales: Steyaert, Jolien, Scheveneels, Wendy, Vanneste, Joni, Van Damme, Philip, Robberecht, Wim, Callaerts, Patrick, Bogaert, Elke, Van Den Bosch, Ludo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240733/
https://www.ncbi.nlm.nih.gov/pubmed/30379317
http://dx.doi.org/10.1093/hmg/ddy303