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FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases characterized by the progressive loss of specific groups of neurons. Due to clinical, genetic and pathological overlap, both diseases are considered as the extremes of one disease spectrum and in a n...
Autores principales: | Steyaert, Jolien, Scheveneels, Wendy, Vanneste, Joni, Van Damme, Philip, Robberecht, Wim, Callaerts, Patrick, Bogaert, Elke, Van Den Bosch, Ludo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240733/ https://www.ncbi.nlm.nih.gov/pubmed/30379317 http://dx.doi.org/10.1093/hmg/ddy303 |
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