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Facile Preparation of Stereoblock PLA From Ring-Opening Polymerization of rac-Lactide by a Synergetic Binary Catalytic System Containing Ureas and Alkoxides
Ring-opening polymerization (ROP) of cyclic esters/lactones by efficient catalysts is a powerful method for synthesis of biodegradable and biocompatible polyesters with well-defined structures. To develop catalytic systems that are fast, selective and controlled is a persistent effort of chemists. I...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240762/ https://www.ncbi.nlm.nih.gov/pubmed/30483495 http://dx.doi.org/10.3389/fchem.2018.00547 |
Sumario: | Ring-opening polymerization (ROP) of cyclic esters/lactones by efficient catalysts is a powerful method for synthesis of biodegradable and biocompatible polyesters with well-defined structures. To develop catalytic systems that are fast, selective and controlled is a persistent effort of chemists. In this contribution, we report a binary urea/alkoxide catalytic system that could catalyze ROP of rac-LA in a fast (over 90% conversion within 1–2 min), stereoselective (P(i) up to 0.93) and controlled manner, indicated by narrow MW distributions, linear relationship between the monomer conversions and M(n)s, end-group fidelity, and chain extension experiments. Remarkably, the catalytic system described here is simple, easily prepared, and structurally tunable and thus has versatile catalytic performances. |
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