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Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc
N-Linked glycopeptides have highly diverse structures in nature. Herein, we describe the first synthesis of rare multi-antennary N-glycan bearing glycan chains on 6-OH of both α1,6- and α1,3-linked mannose arms. To expedite divergent generation of N-glycan structures, four orthogonal protective grou...
Autores principales: | Yang, Weizhun, Ramadan, Sherif, Orwenyo, Jared, Kakeshpour, Tayeb, Diaz, Thomas, Eken, Yigitcan, Sanda, Miloslav, Jackson, James E., Wilson, Angela K., Huang, Xuefei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240809/ https://www.ncbi.nlm.nih.gov/pubmed/30542567 http://dx.doi.org/10.1039/c8sc02457j |
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