hnRNPA2 mediated acetylation reduces telomere length in response to mitochondrial dysfunction

Telomeres protect against chromosomal damage. Accelerated telomere loss has been associated with premature aging syndromes such as Werner’s syndrome and Dyskeratosis Congenita, while, progressive telomere loss activates a DNA damage response leading to chromosomal instability, typically observed in...

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Detalles Bibliográficos
Autores principales: Guha, Manti, Srinivasan, Satish, Johnson, F. Bradley, Ruthel, Gordon, Guja, Kip, Garcia-Diaz, Miguel, Kaufman, Brett A., Glineburg, M. Rebecca, Fang, JiKang, Nakagawa, Hiroshi, Basha, Jeelan, Kundu, Tapas, Avadhani, Narayan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241121/
https://www.ncbi.nlm.nih.gov/pubmed/30427907
http://dx.doi.org/10.1371/journal.pone.0206897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241121/
https://www.ncbi.nlm.nih.gov/pubmed/30427907
http://dx.doi.org/10.1371/journal.pone.0206897

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