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Control of nongenetic heterogeneity in growth rate and stress tolerance of Saccharomyces cerevisiae by cyclic AMP-regulated transcription factors

Genetically identical cells exhibit extensive phenotypic variation even under constant and benign conditions. This so-called nongenetic heterogeneity has important clinical implications: within tumors and microbial infections, cells show nongenetic heterogeneity in growth rate and in susceptibility...

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Detalles Bibliográficos
Autores principales: Li, Shuang, Giardina, Daniella M., Siegal, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241136/
https://www.ncbi.nlm.nih.gov/pubmed/30388117
http://dx.doi.org/10.1371/journal.pgen.1007744

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