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PPARα Enhances Cancer Cell Chemotherapy Sensitivity by Autophagy Induction

PPARα (peroxisome-proliferator-activated receptor α) plays a critical role in regulation of inflammation and cancer, while the regulatory mechanism of PPARα on cancer cell autophagy is still unclear. Here we found that PPARα enhanced autophagy in HEK293T, SW480, and Hela cell lines, which was indepe...

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Detalles Bibliográficos
Autores principales: You, Mengli, Gao, Jiaming, Jin, Jianhua, Hou, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241347/
https://www.ncbi.nlm.nih.gov/pubmed/30519260
http://dx.doi.org/10.1155/2018/6458537

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