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Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality
OBJECTIVE: To investigate the associations between using alternatives to the car which are more active for commuting and non-commuting purposes, and morbidity and mortality. METHODS: We conducted a prospective study using data from 3 58 799 participants, aged 37–73 years, from UK Biobank. Commute an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241630/ https://www.ncbi.nlm.nih.gov/pubmed/29785956 http://dx.doi.org/10.1136/heartjnl-2017-312699 |
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author | Panter, Jenna Mytton, Oliver Sharp, Stephen Brage, Søren Cummins, Steven Laverty, Anthony A Wijndaele, Katrien Ogilvie, David |
author_facet | Panter, Jenna Mytton, Oliver Sharp, Stephen Brage, Søren Cummins, Steven Laverty, Anthony A Wijndaele, Katrien Ogilvie, David |
author_sort | Panter, Jenna |
collection | PubMed |
description | OBJECTIVE: To investigate the associations between using alternatives to the car which are more active for commuting and non-commuting purposes, and morbidity and mortality. METHODS: We conducted a prospective study using data from 3 58 799 participants, aged 37–73 years, from UK Biobank. Commute and non-commute travel were assessed at baseline in 2006–2010. We classified participants according to whether they relied exclusively on the car or used alternative modes of transport that were more active at least some of the time. The main outcome measures were incident cardiovascular disease (CVD) and cancer, and CVD, cancer and all-cause mortality. We excluded events in the first 2 years and conducted analyses separately for those who regularly commuted and those who did not. RESULTS: In maximally adjusted models, regular commuters with more active patterns of travel on the commute had a lower risk of incident (HR 0.89, 95% CI 0.79 to 1.00) and fatal (HR 0.70, 95% CI 0.51 to 0.95) CVD. Those regular commuters who also had more active patterns of non-commute travel had an even lower risk of fatal CVD (HR 0.57, 95% CI 0.39 to 0.85). Among those who were not regular commuters, more active patterns of travel were associated with a lower risk of all-cause mortality (HR 0.92, 95% CI 0.86 to 0.99). CONCLUSIONS: More active patterns of travel were associated with a reduced risk of incident and fatal CVD and all-cause mortality in adults. This is an important message for clinicians advising people about how to be physically active and reduce their risk of disease. |
format | Online Article Text |
id | pubmed-6241630 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-62416302018-11-27 Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality Panter, Jenna Mytton, Oliver Sharp, Stephen Brage, Søren Cummins, Steven Laverty, Anthony A Wijndaele, Katrien Ogilvie, David Heart Cardiac Risk Factors and Prevention OBJECTIVE: To investigate the associations between using alternatives to the car which are more active for commuting and non-commuting purposes, and morbidity and mortality. METHODS: We conducted a prospective study using data from 3 58 799 participants, aged 37–73 years, from UK Biobank. Commute and non-commute travel were assessed at baseline in 2006–2010. We classified participants according to whether they relied exclusively on the car or used alternative modes of transport that were more active at least some of the time. The main outcome measures were incident cardiovascular disease (CVD) and cancer, and CVD, cancer and all-cause mortality. We excluded events in the first 2 years and conducted analyses separately for those who regularly commuted and those who did not. RESULTS: In maximally adjusted models, regular commuters with more active patterns of travel on the commute had a lower risk of incident (HR 0.89, 95% CI 0.79 to 1.00) and fatal (HR 0.70, 95% CI 0.51 to 0.95) CVD. Those regular commuters who also had more active patterns of non-commute travel had an even lower risk of fatal CVD (HR 0.57, 95% CI 0.39 to 0.85). Among those who were not regular commuters, more active patterns of travel were associated with a lower risk of all-cause mortality (HR 0.92, 95% CI 0.86 to 0.99). CONCLUSIONS: More active patterns of travel were associated with a reduced risk of incident and fatal CVD and all-cause mortality in adults. This is an important message for clinicians advising people about how to be physically active and reduce their risk of disease. BMJ Publishing Group 2018-11 2018-05-21 /pmc/articles/PMC6241630/ /pubmed/29785956 http://dx.doi.org/10.1136/heartjnl-2017-312699 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Cardiac Risk Factors and Prevention Panter, Jenna Mytton, Oliver Sharp, Stephen Brage, Søren Cummins, Steven Laverty, Anthony A Wijndaele, Katrien Ogilvie, David Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title | Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title_full | Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title_fullStr | Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title_full_unstemmed | Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title_short | Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
title_sort | using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality |
topic | Cardiac Risk Factors and Prevention |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241630/ https://www.ncbi.nlm.nih.gov/pubmed/29785956 http://dx.doi.org/10.1136/heartjnl-2017-312699 |
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