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A niosome formulation modulates the Th1/Th2 bias immune response in mice and also provides protection against anthrax spore challenge
INTRODUCTION: In this study, we have investigated the immunogenicity and protective efficacy of a niosomal formulation encapsulating protective antigen (PA) and PA domain 4 (D4) of Bacillus anthracis. METHODS: Nonionic surfactant–based vesicles (NISV) + PA and NISV + D4 were prepared from span-60 an...
Autores principales: | Gogoi, Himanshu, Mani, Rajesh, Bhatnagar, Rakesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241689/ https://www.ncbi.nlm.nih.gov/pubmed/30532531 http://dx.doi.org/10.2147/IJN.S153150 |
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