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A niosome formulation modulates the Th1/Th2 bias immune response in mice and also provides protection against anthrax spore challenge

INTRODUCTION: In this study, we have investigated the immunogenicity and protective efficacy of a niosomal formulation encapsulating protective antigen (PA) and PA domain 4 (D4) of Bacillus anthracis. METHODS: Nonionic surfactant–based vesicles (NISV) + PA and NISV + D4 were prepared from span-60 an...

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Detalles Bibliográficos
Autores principales: Gogoi, Himanshu, Mani, Rajesh, Bhatnagar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241689/
https://www.ncbi.nlm.nih.gov/pubmed/30532531
http://dx.doi.org/10.2147/IJN.S153150

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