Decanoic acid attenuates the excitability of nociceptive trigeminal primary and secondary neurons associated with hypoalgesia

BACKGROUND: Acute application of decanoic acid (DA) in vivo suppresses the excitability of spinal trigeminal nucleus caudalis (SpVc) wide dynamic range (WDR) neurons associated with the short-term mechanical hypoalgesia via muscarinic M(2) receptor signaling; however, the effect of DA on nociceptive...

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Detalles Bibliográficos
Autores principales: Nakajima, Ryousuke, Uehara, Airi, Takehana, Shiori, Akama, Youichi, Shimazu, Yoshihito, Takeda, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241697/
https://www.ncbi.nlm.nih.gov/pubmed/30532581
http://dx.doi.org/10.2147/JPR.S181032

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