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Enhanced anticancer activity and intracellular uptake of paclitaxel-containing solid lipid nanoparticles in multidrug-resistant breast cancer cells

PURPOSE: The aim of this study was to show enhanced anticancer activity of paclitaxel (Ptx) incorporated into solid lipid nanoparticles (SLNs) and reveal reversal of multidrug resistance (MDR) by SLNs mediated by increased uptake through different entry mechanisms from that in drug-sensitive cells....

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Detalles Bibliográficos
Autores principales:	Xu, Wenting, Bae, Eun Ju, Lee, Mi-Kyung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241869/ https://www.ncbi.nlm.nih.gov/pubmed/30532538 http://dx.doi.org/10.2147/IJN.S182621

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