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Similar dysregulation of lupus-associated miRNAs in peripheral blood mononuclear cells and splenic lymphocytes in MRL/lpr mice

OBJECTIVE: MicroRNAs (miRNAs) play an important role in the pathogenesis of various autoimmune diseases including systemic lupus erythematosus (SLE; lupus). We have previously reported a common pattern of miRNA dysregulation in splenic lymphocytes from several mouse models of lupus. In this study, w...

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Detalles Bibliográficos
Autores principales: Wang, Zhuang, Heid, Bettina, Dai, Rujuan, Ahmed, Sattar Ansar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241985/
https://www.ncbi.nlm.nih.gov/pubmed/30515297
http://dx.doi.org/10.1136/lupus-2018-000290