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Vitamin D status in South Korean population: Seven-year trend from the KNHANES
Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia. We performed an observational study to investigate the trend of vitamin D status in South Korea based on a representa...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242298/ https://www.ncbi.nlm.nih.gov/pubmed/29952942 http://dx.doi.org/10.1097/MD.0000000000011032 |
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author | Park, Ju-Hyun Hong, In Young Chung, Jae Woo Choi, Han Seok |
author_facet | Park, Ju-Hyun Hong, In Young Chung, Jae Woo Choi, Han Seok |
author_sort | Park, Ju-Hyun |
collection | PubMed |
description | Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia. We performed an observational study to investigate the trend of vitamin D status in South Korea based on a representative national database acquired from the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2008 to 2014. A total of 39,759 patients were included in the final analyses. Serum 25-hydroxyvitamin D (25 (OH)D) levels were measured by radioimmunoassay. The overall mean serum level of 25 (OH)D was 45.7 nmol/L in males and 40.9 nmol/L in females in KNHANES 2008 to 2014. There was a significant trend toward lower serum 25 (OH)D levels from 2008 to 2014 in males by −1.2 (95% confidence interval [CI] −1.5 to −0.9) nmol/L per year and in female by −0.7 (95% CI −0.9 to −0.4) nmol/L per year. The overall mean serum level of 25 (OH)D in 2008 was 53.0 nmol/L in males and 45.7 nmol/L in females. It decreased to 43.2 nmol/L in males and 39.2 nmol/L in females in 2014. Vitamin D deficiency, defined as the serum 25 (OH)D level of <50 nmol/L, was found in 65.7% of males and 76.7% of females in overall population. A significant increasing trend of vitamin D deficiency was also observed. The prevalence of vitamin D deficiency in 2008 was 51.8% in males and 68.2% in females, but rose to 75.2% and 82.5%, respectively, in 2014. The present study demonstrated that vitamin D status in South Koreans is still deteriorating. More extensive and proactive measures are needed to improve vitamin D status in South Korea. |
format | Online Article Text |
id | pubmed-6242298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-62422982018-12-07 Vitamin D status in South Korean population: Seven-year trend from the KNHANES Park, Ju-Hyun Hong, In Young Chung, Jae Woo Choi, Han Seok Medicine (Baltimore) Research Article Vitamin D deficiency has become one of the most prevalent health problems in modern society. However, there has been no study that has reported the trend of vitamin D status in Asia. We performed an observational study to investigate the trend of vitamin D status in South Korea based on a representative national database acquired from the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2008 to 2014. A total of 39,759 patients were included in the final analyses. Serum 25-hydroxyvitamin D (25 (OH)D) levels were measured by radioimmunoassay. The overall mean serum level of 25 (OH)D was 45.7 nmol/L in males and 40.9 nmol/L in females in KNHANES 2008 to 2014. There was a significant trend toward lower serum 25 (OH)D levels from 2008 to 2014 in males by −1.2 (95% confidence interval [CI] −1.5 to −0.9) nmol/L per year and in female by −0.7 (95% CI −0.9 to −0.4) nmol/L per year. The overall mean serum level of 25 (OH)D in 2008 was 53.0 nmol/L in males and 45.7 nmol/L in females. It decreased to 43.2 nmol/L in males and 39.2 nmol/L in females in 2014. Vitamin D deficiency, defined as the serum 25 (OH)D level of <50 nmol/L, was found in 65.7% of males and 76.7% of females in overall population. A significant increasing trend of vitamin D deficiency was also observed. The prevalence of vitamin D deficiency in 2008 was 51.8% in males and 68.2% in females, but rose to 75.2% and 82.5%, respectively, in 2014. The present study demonstrated that vitamin D status in South Koreans is still deteriorating. More extensive and proactive measures are needed to improve vitamin D status in South Korea. Wolters Kluwer Health 2018-06-29 /pmc/articles/PMC6242298/ /pubmed/29952942 http://dx.doi.org/10.1097/MD.0000000000011032 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-nc-sa/4.0 |
spellingShingle | Research Article Park, Ju-Hyun Hong, In Young Chung, Jae Woo Choi, Han Seok Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title | Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title_full | Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title_fullStr | Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title_full_unstemmed | Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title_short | Vitamin D status in South Korean population: Seven-year trend from the KNHANES |
title_sort | vitamin d status in south korean population: seven-year trend from the knhanes |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242298/ https://www.ncbi.nlm.nih.gov/pubmed/29952942 http://dx.doi.org/10.1097/MD.0000000000011032 |
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