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Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation

Allogeneic hematopoietic cell transplantation is often complicated by graft versus host disease (GvHD), primarily mediated through allo-reactive donor T cells in the donor stem cell graft. Enhancer of Zeste Homolog 2 (EZH2), a histone-lysine N-methyltransferase and a component of the Polycomb Repres...

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Detalles Bibliográficos
Autores principales:	Alahmari, Bader, Cooper, Matthew, Ziga, Edward, Ritchey, Julie, DiPersio, John F., Choi, Jaebok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242356/ https://www.ncbi.nlm.nih.gov/pubmed/30452487 http://dx.doi.org/10.1371/journal.pone.0207609

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