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Expression of two non-mutated genetic elements is sufficient to stimulate oncogenic transformation of human mammary epithelial cells

Trefoil factor 3 (TFF3) expression is positively associated with advanced clinicopathological features of mammary carcinoma (MC). Herein, we provide evidence for a functional role of TFF3 in oncogenic transformation of immortalized, but otherwise normal human mammary epithelial cells (HMECs), namely...

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Detalles Bibliográficos
Autores principales: Pandey, Vijay, Zhang, Min, You, Mingliang, Zhang, Weijie, Chen, Rumei, Zhang, Wei, Ma, Lan, Wu, Zheng-Sheng, Zhu, Tao, Xu, Xiu Qin, Lobie, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242831/
https://www.ncbi.nlm.nih.gov/pubmed/30451834
http://dx.doi.org/10.1038/s41419-018-1177-6