Cargando…

Expression of two non-mutated genetic elements is sufficient to stimulate oncogenic transformation of human mammary epithelial cells

Trefoil factor 3 (TFF3) expression is positively associated with advanced clinicopathological features of mammary carcinoma (MC). Herein, we provide evidence for a functional role of TFF3 in oncogenic transformation of immortalized, but otherwise normal human mammary epithelial cells (HMECs), namely...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandey, Vijay, Zhang, Min, You, Mingliang, Zhang, Weijie, Chen, Rumei, Zhang, Wei, Ma, Lan, Wu, Zheng-Sheng, Zhu, Tao, Xu, Xiu Qin, Lobie, Peter E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242831/ https://www.ncbi.nlm.nih.gov/pubmed/30451834 http://dx.doi.org/10.1038/s41419-018-1177-6

Ejemplares similares

Hypomethylation associated enhanced transcription of trefoil factor-3 mediates tamoxifen-stimulated oncogenicity of ER+ endometrial carcinoma cells
por: Pandey, Vijay, et al.
Publicado: (2017)

Autocrine hGH stimulates oncogenicity, epithelial-mesenchymal transition and cancer stem cell-like behavior in human colorectal carcinoma
por: Wang, Jing-Jing, et al.
Publicado: (2017)

Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation
por: Dunphy, Karen A, et al.
Publicado: (2013)

Trefoil factor 3 promotes metastatic seeding and predicts poor survival outcome of patients with mammary carcinoma
por: Pandey, Vijay, et al.
Publicado: (2014)

Trefoil Factor-3 (TFF3) Stimulates De Novo Angiogenesis in Mammary Carcinoma both Directly and Indirectly via IL-8/CXCR2
por: Lau, Wai-Hoe, et al.
Publicado: (2015)

Prognostic significance of the expression of GFRα1, GFRα3 and Syndecan-3, proteins binding ARTEMIN, in mammary carcinoma
por: Wu, Zheng-Sheng, et al.
Publicado: (2013)

Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent
por: You, Ming-Liang, et al.
Publicado: (2017)

Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction
por: Ito, Reina E., et al.
Publicado: (2021)

Distinct Oncogenic Transcriptomes in Human Mammary Epithelial Cells Infected With Cytomegalovirus
por: Haidar Ahmad, Sandy, et al.
Publicado: (2021)

ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma
por: Banerjee, Arindam, et al.
Publicado: (2011)

Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells
por: Liu, Zhao, et al.
Publicado: (2016)

Release of HER2 repression of trefoil factor 3 (TFF3) expression mediates trastuzumab resistance in HER2+/ER+ mammary carcinoma
por: Chong, Qing-Yun, et al.
Publicado: (2017)

Novel Biphenyl Amines Inhibit Oestrogen Receptor (ER)-α in ER-Positive Mammary Carcinoma Cells
por: Basappa, Basappa, et al.
Publicado: (2021)

ARTEMIN Promotes Oncogenicity and Resistance to 5-Fluorouracil in Colorectal Carcinoma by p44/42 MAPK Dependent Expression of CDH2
por: Zhuang, Qiu-Shi, et al.
Publicado: (2021)

Adipocyte-derived kynurenine stimulates malignant transformation of mammary epithelial cells through the aryl hydrocarbon receptor
por: Diedrich, Jonathan D., et al.
Publicado: (2023)

Alteration of oestradiol metabolism in myc oncogene-transfected mouse mammary epithelial cells.
por: Telang, N. T., et al.
Publicado: (1998)

The Human Cytomegalovirus Strain DB Activates Oncogenic Pathways in Mammary Epithelial Cells
por: Kumar, Amit, et al.
Publicado: (2018)

Wnt4 is not sufficient to induce lobuloalveolar mammary development
por: Kim, Young Chul, et al.
Publicado: (2009)

Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma
por: Zhang, Min, et al.
Publicado: (2015)

Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition
por: Park, Jeongsook, et al.
Publicado: (2013)

Oxidized LDL Triggers Pro-Oncogenic Signaling in Human Breast Mammary Epithelial Cells Partly via Stimulation of MiR-21
por: Khaidakov, Magomed, et al.
Publicado: (2012)

CXC Chemokine Signaling in Progression of Epithelial Ovarian Cancer: Theranostic Perspectives
por: Huang, Xinxin, et al.
Publicado: (2022)

Oncogenic Potential of Bisphenol A and Common Environmental Contaminants in Human Mammary Epithelial Cells
por: Nair, Vidhya A, et al.
Publicado: (2020)

Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
por: Senapati, Parijat, et al.
Publicado: (2023)

Constitutive CCND1/CDK2 Activity Substitutes for p53 Loss, or MYC or Oncogenic RAS Expression in the Transformation of Human Mammary Epithelial Cells
por: Junk, Damian J., et al.
Publicado: (2013)

Investigation of NPB Analogs That Target Phosphorylation of BAD-Ser99 in Human Mammary Carcinoma Cells
por: Girimanchanaika, Swamy Savvemala, et al.
Publicado: (2021)

The transcriptome of human mammary epithelial cells infected with the HCMV-DB strain displays oncogenic traits
por: Moussawi, Fatima Al, et al.
Publicado: (2018)

Metabolomic Profiles of Bovine Mammary Epithelial Cells Stimulated by Lipopolysaccharide
por: Huang, Yixin, et al.
Publicado: (2019)

Inhibition of TFF3 Enhances Sensitivity—and Overcomes Acquired Resistance—to Doxorubicin in Estrogen Receptor-Positive Mammary Carcinoma
por: Poh, Han Ming, et al.
Publicado: (2019)

Mammary epithelial cell transformation: insights from cell culture and mouse models
por: Dimri, Goberdhan, et al.
Publicado: (2005)

Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo
por: Rowson-Hodel, A. R., et al.
Publicado: (2015)

Epstein–Barr Virus Infection of Mammary Epithelial Cells Promotes Malignant Transformation()
por: Hu, Hai, et al.
Publicado: (2016)

Luminal Epithelial Cells within the Mammary Gland Can Produce Basal Cells upon Oncogenic Stress
por: Hein, Sarah M., et al.
Publicado: (2015)

B-cell lymphoma 6 protein stimulates oncogenicity of human breast cancer cells
por: Wu, Qiang, et al.
Publicado: (2014)

Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2
por: Tan, Sheng, et al.
Publicado: (2014)

Oncogenic role of epithelial cell transforming sequence 2 in lung adenocarcinoma cells
por: Tan, Hongyi, et al.
Publicado: (2016)

Oncogenic transformation of normal breast epithelial cells co-cultured with cancer cells
por: Li, Song, et al.
Publicado: (2018)

Oncogenic role of epithelial cell transforming sequence 2 in lung adenocarcinoma cells
por: Tan, Hongyi, et al.
Publicado: (2021)

Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells
por: Lin, Shu, et al.
Publicado: (2012)

Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells
por: Rao, Krishna, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_6p5e04cmocr5qsla73nnsua0m0