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RIG-I like receptor sensing of host RNAs facilitates the cell-intrinsic immune response to KSHV infection

The RIG-I like receptors (RLRs) RIG-I and MDA5 are cytosolic RNA helicases best characterized as restriction factors for RNA viruses. However, evidence suggests RLRs participate in innate immune recognition of other pathogens, including DNA viruses. Kaposi’s sarcoma-associated herpesvirus (KSHV) is...

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Detalles Bibliográficos
Autores principales:	Zhao, Yang, Ye, Xiang, Dunker, William, Song, Yu, Karijolich, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242832/ https://www.ncbi.nlm.nih.gov/pubmed/30451863 http://dx.doi.org/10.1038/s41467-018-07314-7

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