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Sequences encoding C2H2 zinc fingers inhibit polyadenylation and mRNA export in human cells

The large C2H2-Zinc Finger (C2H2-ZNF) gene family has rapidly expanded in primates through gene duplication. There is consequently considerable sequence homology between family members at both the nucleotide and amino acid level, allowing for coordinated regulation and shared functions. Here we show...

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Detalles Bibliográficos
Autores principales: Russo, Joseph, Jalkanen, Aimee L., Heck, Adam M., Schmidt, Caleb M., Wilusz, Jeffrey, Wilusz, Carol J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242934/
https://www.ncbi.nlm.nih.gov/pubmed/30451889
http://dx.doi.org/10.1038/s41598-018-35138-4