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Contribution of p62/SQSTM1 to PDGF-BB-induced myofibroblast-like phenotypic transition in vascular smooth muscle cells lacking Smpd1 gene
Accumulating evidence indicates a critical role of autophagy in regulating vascular smooth muscle cell (SMC) homeostasis in atherogenesis. However, little is known about the modulatory role of autophagy in PDGF-BB-induced SMC transition towards the synthetic phenotype and extracellular matrix remode...
Autores principales: | Zhang, Peng, Guan, Yinglu, Chen, Jiajie, Li, Xiang, McConnell, Bradley K., Zhou, Wei, Boini, Krishna M., Zhang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242941/ https://www.ncbi.nlm.nih.gov/pubmed/30451833 http://dx.doi.org/10.1038/s41419-018-1197-2 |
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