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The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity

Interleukin-33 (IL-33) is a IL-1 family member of cytokines exerting pleiotropic activities. In the steady-state, IL-33 is expressed in the nucleus of epithelial, endothelial, and fibroblast-like cells acting as a nuclear protein. In response to tissue damage, infections or necrosis IL-33 is release...

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Detalles Bibliográficos
Autores principales: Afferni, Claudia, Buccione, Carla, Andreone, Sara, Galdiero, Maria Rosaria, Varricchi, Gilda, Marone, Gianni, Mattei, Fabrizio, Schiavoni, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242976/
https://www.ncbi.nlm.nih.gov/pubmed/30483263
http://dx.doi.org/10.3389/fimmu.2018.02601