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Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy

Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal cancer (CRC) patients. The role of the differentially expressed lncRNAs in 5-Fluorouracil chemoresistance has not fully explained. Here, we observed lncRNA H19 was associated with the 5-Fu resistance in CRC. Quant...

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Detalles Bibliográficos
Autores principales:	Wang, Meng, Han, Dong, Yuan, Ziming, Hu, Hanqing, Zhao, Zhixun, Yang, Runkun, Jin, Yinghu, Zou, Chaoxia, Chen, Yinggang, Wang, Guiyu, Gao, Xu, Wang, Xishan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242979/ https://www.ncbi.nlm.nih.gov/pubmed/30451820 http://dx.doi.org/10.1038/s41419-018-1187-4

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