Cargando…

Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease

Calcinosis is frequently associated with systemic sclerosis (SSc) and can be located at various sites, although it is most commonly seen in the hands. When it presents around the synovial joints and is associated with a mass-like appearance, it is classically called tumoral calcinosis. Few cases of...

Descripción completa

Detalles Bibliográficos
Autores principales: Liberato, Afonso Celso Pedrotti, Amaral, Lazaro Luiz Faria Do, Marussi, Victor Hugo Rocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243371/
https://www.ncbi.nlm.nih.gov/pubmed/30459985
http://dx.doi.org/10.1259/bjrcr.20150435
_version_ 1783371969447591936
author Liberato, Afonso Celso Pedrotti
Amaral, Lazaro Luiz Faria Do
Marussi, Victor Hugo Rocha
author_facet Liberato, Afonso Celso Pedrotti
Amaral, Lazaro Luiz Faria Do
Marussi, Victor Hugo Rocha
author_sort Liberato, Afonso Celso Pedrotti
collection PubMed
description Calcinosis is frequently associated with systemic sclerosis (SSc) and can be located at various sites, although it is most commonly seen in the hands. When it presents around the synovial joints and is associated with a mass-like appearance, it is classically called tumoral calcinosis. Few cases of tumoral calcinosis have been reported in the paraspinal region. They are usually located in the cervical segment and rarely in the lumbar region. Occasionally, they have been associated with nerve root compression and intraspinal extension. We report the case of a 47-year-old female with advanced SSc who presented to our hospital’s radiology department with chronic low back pain and right L5 radiculopathy due to tumoral calcinosis. An initial lumbar spine MRI showed multifocal, low signal, mass-like lesions involving the right paraspinal soft tissues. At the L5–S1 level, one lesion compressed the right L5 exiting nerve root. A CT scan of the lumbar spine performed later demonstrated the calcified nature of the lesions depicted by MRI and evidenced signs of pulmonary fibrosis at the base of the lungs. Further clinical work-up also showed that the patient had Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, dyspnoea, facial telangiectasias, generalized weakness and arthralgia. The diagnosis of a subtype of SSc, called limited cutaneous SSc, was made. Our case describes the CT and MRI findings of tumoral calcinosis in an unusual location secondary to limited cutaneous SSc. Knowledge of the imaging features of this uncommon manifestation of SSc could potentially increase its prospective diagnosis and hence improve patient management.
format Online
Article
Text
id pubmed-6243371
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher The British Institute of Radiology
record_format MEDLINE/PubMed
spelling pubmed-62433712018-11-20 Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease Liberato, Afonso Celso Pedrotti Amaral, Lazaro Luiz Faria Do Marussi, Victor Hugo Rocha BJR Case Rep Case Report Calcinosis is frequently associated with systemic sclerosis (SSc) and can be located at various sites, although it is most commonly seen in the hands. When it presents around the synovial joints and is associated with a mass-like appearance, it is classically called tumoral calcinosis. Few cases of tumoral calcinosis have been reported in the paraspinal region. They are usually located in the cervical segment and rarely in the lumbar region. Occasionally, they have been associated with nerve root compression and intraspinal extension. We report the case of a 47-year-old female with advanced SSc who presented to our hospital’s radiology department with chronic low back pain and right L5 radiculopathy due to tumoral calcinosis. An initial lumbar spine MRI showed multifocal, low signal, mass-like lesions involving the right paraspinal soft tissues. At the L5–S1 level, one lesion compressed the right L5 exiting nerve root. A CT scan of the lumbar spine performed later demonstrated the calcified nature of the lesions depicted by MRI and evidenced signs of pulmonary fibrosis at the base of the lungs. Further clinical work-up also showed that the patient had Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, dyspnoea, facial telangiectasias, generalized weakness and arthralgia. The diagnosis of a subtype of SSc, called limited cutaneous SSc, was made. Our case describes the CT and MRI findings of tumoral calcinosis in an unusual location secondary to limited cutaneous SSc. Knowledge of the imaging features of this uncommon manifestation of SSc could potentially increase its prospective diagnosis and hence improve patient management. The British Institute of Radiology 2016-07-28 /pmc/articles/PMC6243371/ /pubmed/30459985 http://dx.doi.org/10.1259/bjrcr.20150435 Text en © 2016 The Authors. Published by the British Institute of Radiology http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Liberato, Afonso Celso Pedrotti
Amaral, Lazaro Luiz Faria Do
Marussi, Victor Hugo Rocha
Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title_full Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title_fullStr Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title_full_unstemmed Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title_short Tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
title_sort tumoral calcinosis in the lumbar spine secondary to systemic sclerosis: a rare cause of radiculopathy in an adult with advanced disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243371/
https://www.ncbi.nlm.nih.gov/pubmed/30459985
http://dx.doi.org/10.1259/bjrcr.20150435
work_keys_str_mv AT liberatoafonsocelsopedrotti tumoralcalcinosisinthelumbarspinesecondarytosystemicsclerosisararecauseofradiculopathyinanadultwithadvanceddisease
AT amarallazaroluizfariado tumoralcalcinosisinthelumbarspinesecondarytosystemicsclerosisararecauseofradiculopathyinanadultwithadvanceddisease
AT marussivictorhugorocha tumoralcalcinosisinthelumbarspinesecondarytosystemicsclerosisararecauseofradiculopathyinanadultwithadvanceddisease