Tacrine(10)-Hupyridone Prevents Post-operative Cognitive Dysfunction via the Activation of BDNF Pathway and the Inhibition of AChE in Aged Mice

Post-operative cognitive dysfunction (POCD) could cause short-term or long-term cognitive disruption lasting weeks or months after anesthesia and surgery in elderly. However, no effective treatment of POCD is currently available. Previous studies indicated that the enhancement of brain-derived neuro...

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Detalles Bibliográficos
Autores principales: Chen, Huixin, Wu, Xiang, Gu, Xinmei, Zhou, Yiying, Ye, Luying, Zhang, Ke, Pan, Hanbo, Wang, Jialing, Wei, Hua, Zhu, Binbin, Naman, C. Benjamin, Mak, Shinghung, Carlier, Paul R., Cui, Wei, Han, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243707/
https://www.ncbi.nlm.nih.gov/pubmed/30483056
http://dx.doi.org/10.3389/fncel.2018.00396

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