Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule

G-quadruplexes (G4) are secondary nucleic acid structures that have been associated with genomic instability and cancer progression. When present in the promoter of some oncogenes, G4 structures can affect gene regulation and, hence, represent a possible therapeutic target. In this study, RNA-Seq wa...

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Detalles Bibliográficos
Autores principales: Zorzan, Eleonora, Elgendy, Ramy, Giantin, Mery, Dacasto, Mauro, Sissi, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244004/
https://www.ncbi.nlm.nih.gov/pubmed/30459395
http://dx.doi.org/10.1038/s41598-018-35516-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244004/
https://www.ncbi.nlm.nih.gov/pubmed/30459395
http://dx.doi.org/10.1038/s41598-018-35516-y

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