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Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule
G-quadruplexes (G4) are secondary nucleic acid structures that have been associated with genomic instability and cancer progression. When present in the promoter of some oncogenes, G4 structures can affect gene regulation and, hence, represent a possible therapeutic target. In this study, RNA-Seq wa...
Autores principales: | Zorzan, Eleonora, Elgendy, Ramy, Giantin, Mery, Dacasto, Mauro, Sissi, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244004/ https://www.ncbi.nlm.nih.gov/pubmed/30459395 http://dx.doi.org/10.1038/s41598-018-35516-y |
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