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Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function

Despite the addition of cystic fibrosis transmembrane conductance regulator (CFTR) modulators to the cystic fibrosis (CF) treatment regimen, patients with CF continue to suffer from chronic bacterial infections that lead to progressive respiratory morbidity. Host immunity, and macrophage dysfunction...

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Detalles Bibliográficos
Autores principales: Zhang, Shuzhong, Shrestha, Chandra L., Kopp, Benjamin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244248/
https://www.ncbi.nlm.nih.gov/pubmed/30459435
http://dx.doi.org/10.1038/s41598-018-35151-7