PRL2 Controls Phagocyte Bactericidal Activity by Sensing and Regulating ROS

Although it is well-recognized that inflammation enhances leukocyte bactericidal activity, the underlying mechanisms are not clear. Here we report that PRL2 is sensitive to oxidative stress at inflamed sites. Reduced PRL2 in phagocytes causes increased respiratory burst activity and enhances phagocy...

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Detalles Bibliográficos
Autores principales: Yin, Cennan, Wu, Chenyun, Du, Xinyue, Fang, Yan, Pu, Juebiao, Wu, Jianhua, Tang, Lili, Zhao, Wei, Weng, Yongqiang, Guo, Xiaokui, Chen, Guangjie, Wang, Zhaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244668/
https://www.ncbi.nlm.nih.gov/pubmed/30483267
http://dx.doi.org/10.3389/fimmu.2018.02609

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