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Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice

Nesprin-2 is a nuclear envelope component and provides a link between cytoskeletal components of the cytoplasm and the nucleoplasm. Several isoforms are generated from its gene Syne2. Loss of the largest isoform Nesprin-2 Giant in mice is associated with a skin phenotype and altered wound healing, l...

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Detalles Bibliográficos
Autores principales: Mroß, Carmen, Marko, Marija, Munck, Martina, Glöckner, Gernot, Motameny, Susanne, Altmüller, Janine, Noegel, Angelika A., Eichinger, Ludwig, Peche, Vivek S., Neumann, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244730/
https://www.ncbi.nlm.nih.gov/pubmed/30220251
http://dx.doi.org/10.1080/19491034.2018.1523664