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Simulation-based suggestions to improve ibuprofen dosing for patent ductus arteriosus in preterm newborns

PURPOSE: Ibuprofen is the drug of choice for treatment of patent ductus arteriosus (PDA). There is accumulating evidence that current ibuprofen-dosing regimens for PDA treatment are inadequate. We aimed to propose an improved dosing regimen, based on all current knowledge. METHODS: We performed a li...

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Detalles Bibliográficos
Autores principales:	Flint, Robert B., ter Heine, Rob, Spaans, Edwin, Burger, David M., de Klerk, Johan C. A., Allegaert, Karel, Knibbe, Catherijne A. J., Simons, Sinno H. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Pharmacokinetics and Disposition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244763/ https://www.ncbi.nlm.nih.gov/pubmed/30054639 http://dx.doi.org/10.1007/s00228-018-2529-y

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