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Fotemustine, teniposide and dexamethasone versus high-dose methotrexate plus cytarabine in newly diagnosed primary CNS lymphoma: a randomised phase 2 trial

OBJECTIVE: This prospective, randomized, controlled and open-label clinical trial sought to evaluate the tolerability and efficacy of the FTD regimen (fotemustine, teniposide and dexamethasone) compared to HD-MA therapy (high-dose methotrexate plus cytarabine) and to elucidate some biomarkers that i...

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Detalles Bibliográficos
Autores principales: Wu, Jingjing, Duan, Lingling, Zhang, Lei, Sun, Zhenchang, Fu, Xiaorui, Li, Xin, Li, Ling, Wang, Xinhua, Zhang, Xudong, Li, Zhaoming, Yu, Hui, Chang, Yu, Nan, Feifei, Yan, Jiaqin, Tian, Li, Wang, Xiaoli, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244785/
https://www.ncbi.nlm.nih.gov/pubmed/30109672
http://dx.doi.org/10.1007/s11060-018-2970-x