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Studies with β-Oxoalkanonitriles: Simple Novel Synthesis of 3-[2,6-Diaryl-4- pyridyl]-3-oxopropanenitriles

Heteroaromatization of ethyl 2-cyano-4-oxo-2-(2-oxo-2-arylethyl)-4-aryl-butanoates 3a,b with ammonium acetate gave ethyl 2,6-diarylisonicotinates 4a,b.Treatment of the latter with acetonitrile afforded novel β-oxoalkanonitriles 6a,b. Reactions of 6a,b with phenyl hydrazine and hydroxylamine gave the...

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Detalles Bibliográficos
Autores principales:	Riyadh, Sayed M., Al-Matar, Hamad M., Elnagdi, Mohamed H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244831/ https://www.ncbi.nlm.nih.gov/pubmed/19078855 http://dx.doi.org/10.3390/molecules13123140

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