Synthesis and Antiproliferative Activities of 5-Azacytidine Analogues in Human Leukemia Cells

Twenty-six 5-azacytidine analogues have been synthesized, including 4-amino-6-alkyl-1-pyranosyl/ribofuranosyl-1,3,5-triazin-2(1H)-ones 1a-j, 6-amino-4-alkyl/aryl-1-pyranosyl/ribofuranosyl-1,3,5-triazin-2(1H)-ones 2a-f and 4-amino-6-alkyl-1,3,5-triazin-2-yl-1-thio-pyranosides/ribofuranosides 3a-j. Th...

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Detalles Bibliográficos
Autores principales: Guo, Gang, Li, Gang, Liu, Dan, Yang, Qian-jiao, Liu, Yu, Jing, Yong-kui, Zhao, Lin-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244837/
https://www.ncbi.nlm.nih.gov/pubmed/18719520
http://dx.doi.org/10.3390/molecules13071487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244837/
https://www.ncbi.nlm.nih.gov/pubmed/18719520
http://dx.doi.org/10.3390/molecules13071487

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