Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole

4-Methyl-5-formylthiazole, an intermediate for synthesizing cefditoren pivoxil, was prepared in good yield by Pd/BaSO(4) catalyzed hydrogenation of 4-methylthiazole-5-carboxylic acid chloride. Detailed reaction conditions have been studied.

Detalles Bibliográficos
Autores principales: Bai, Nan, Sha, Yaowu, Meng, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244845/
https://www.ncbi.nlm.nih.gov/pubmed/18463596
http://dx.doi.org/10.3390/molecules13040943
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author Bai, Nan
Sha, Yaowu
Meng, Ge
author_facet Bai, Nan
Sha, Yaowu
Meng, Ge
author_sort Bai, Nan
collection PubMed
description 4-Methyl-5-formylthiazole, an intermediate for synthesizing cefditoren pivoxil, was prepared in good yield by Pd/BaSO(4) catalyzed hydrogenation of 4-methylthiazole-5-carboxylic acid chloride. Detailed reaction conditions have been studied.
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spelling pubmed-62448452018-11-26 Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole Bai, Nan Sha, Yaowu Meng, Ge Molecules Communication 4-Methyl-5-formylthiazole, an intermediate for synthesizing cefditoren pivoxil, was prepared in good yield by Pd/BaSO(4) catalyzed hydrogenation of 4-methylthiazole-5-carboxylic acid chloride. Detailed reaction conditions have been studied. MDPI 2008-04-21 /pmc/articles/PMC6244845/ /pubmed/18463596 http://dx.doi.org/10.3390/molecules13040943 Text en © 2008 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Communication
Bai, Nan
Sha, Yaowu
Meng, Ge
Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title_full Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title_fullStr Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title_full_unstemmed Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title_short Efficient and Eco-Friendly Preparation of4-Methyl-5-formyl-thiazole
title_sort efficient and eco-friendly preparation of4-methyl-5-formyl-thiazole
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244845/
https://www.ncbi.nlm.nih.gov/pubmed/18463596
http://dx.doi.org/10.3390/molecules13040943
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