Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a risk factor for type 2 diabetes. Our aim was to investigate the relationship between NAFLD and impaired glucose metabolism in terms of insulin receptor substrate 1 and 2 (IRS1 and IRS2) expression in the liver. METHODS: Liver biopsy was perfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Enooku, Kenichiro, Kondo, Mayuko, Fujiwara, Naoto, Sasako, Takayoshi, Shibahara, Junji, Kado, Akira, Okushin, Kazuya, Fujinaga, Hidetaka, Tsutsumi, Takeya, Nakagomi, Ryo, Minami, Tatsuya, Sato, Masaya, Nakagawa, Hayato, Kondo, Yuji, Asaoka, Yoshinari, Tateishi, Ryosuke, Ueki, Kohjiro, Ikeda, Hitoshi, Yoshida, Haruhiko, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Kadowaki, Takashi, Fukayama, Masashi, Koike, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2018
Materias:
Original Article—Liver, Pancreas, and Biliary Tract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244858/
https://www.ncbi.nlm.nih.gov/pubmed/29749571
http://dx.doi.org/10.1007/s00535-018-1472-0

Ejemplares similares

Ejemplares similares