Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate

A general method for the preparation of bis-ureas from bis(o-nitrophenyl) carbonate has been developed. Directional urea synthesis is achieved by sequential amine addition to bis(o-nitrophenyl) carbonate in two steps: in the first step bis(o-nitrophenyl) carbonate is reacted with benzylamine to form...

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Detalles Bibliográficos
Autores principales: Turoczi, Maria-Cristina, Simon, Monika, Badea, Valentin, Csunderlik, Carol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244956/
https://www.ncbi.nlm.nih.gov/pubmed/19078859
http://dx.doi.org/10.3390/molecules13123192
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author Turoczi, Maria-Cristina
Simon, Monika
Badea, Valentin
Csunderlik, Carol
author_facet Turoczi, Maria-Cristina
Simon, Monika
Badea, Valentin
Csunderlik, Carol
author_sort Turoczi, Maria-Cristina
collection PubMed
description A general method for the preparation of bis-ureas from bis(o-nitrophenyl) carbonate has been developed. Directional urea synthesis is achieved by sequential amine addition to bis(o-nitrophenyl) carbonate in two steps: in the first step bis(o-nitrophenyl) carbonate is reacted with benzylamine to form benzyl-o-nitrophenyl carbamate; in the second step the carbamate is reacted with a variety of diamines in toluene to yield bis-ureas.
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spelling pubmed-62449562018-11-26 Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate Turoczi, Maria-Cristina Simon, Monika Badea, Valentin Csunderlik, Carol Molecules Article A general method for the preparation of bis-ureas from bis(o-nitrophenyl) carbonate has been developed. Directional urea synthesis is achieved by sequential amine addition to bis(o-nitrophenyl) carbonate in two steps: in the first step bis(o-nitrophenyl) carbonate is reacted with benzylamine to form benzyl-o-nitrophenyl carbamate; in the second step the carbamate is reacted with a variety of diamines in toluene to yield bis-ureas. MDPI 2008-12-15 /pmc/articles/PMC6244956/ /pubmed/19078859 http://dx.doi.org/10.3390/molecules13123192 Text en © 2008 by the authors. Licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Turoczi, Maria-Cristina
Simon, Monika
Badea, Valentin
Csunderlik, Carol
Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title_full Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title_fullStr Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title_full_unstemmed Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title_short Synthesis of Bis-ureas from Bis(o-nitrophenyl) Carbonate
title_sort synthesis of bis-ureas from bis(o-nitrophenyl) carbonate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6244956/
https://www.ncbi.nlm.nih.gov/pubmed/19078859
http://dx.doi.org/10.3390/molecules13123192
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