Design, Synthesis, and Antitumor Activities of Some Novel Substituted 1,2,3-Benzotriazines

A series of novel substituted 1,2,3-benzotriazines based on the structures of vatalanib succinate (PTK787) and vandetanib (ZD6474) were designed and synthesized. The antiproliferative effects of these compounds were tested on microvascular endothelial cells (MVECs) using the MTT assay. Introduction...

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Detalles Bibliográficos
Autores principales: Lv, Jin-Ling, Wang, Rui, Liu, Dan, Guo, Gang, Jing, Yong-Kui, Zhao, Lin-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245182/
https://www.ncbi.nlm.nih.gov/pubmed/18596667
http://dx.doi.org/10.3390/molecules13061427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245182/
https://www.ncbi.nlm.nih.gov/pubmed/18596667
http://dx.doi.org/10.3390/molecules13061427

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