Radiation- and Photo-induced Activation of 5-Fluorouracil Prodrugs as a Strategy for the Selective Treatment of Solid Tumors

5-Fluorouracil (5-FU) is used widely as an anticancer drug to treat solid cancers, such as colon, breast, rectal, and pancreatic cancers, although its clinical application is limited because 5-FU has gastrointestinal and hematological toxicity. Many groups are searching for prodrugs with functions t...

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Detalles Bibliográficos
Autores principales: Ito, Takeo, Tanabe, Kazuhito, Yamada, Hisatsugu, Hatta, Hiroshi, Nishimoto, Sei-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245186/
https://www.ncbi.nlm.nih.gov/pubmed/18830160
http://dx.doi.org/10.3390/molecules13102370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245186/
https://www.ncbi.nlm.nih.gov/pubmed/18830160
http://dx.doi.org/10.3390/molecules13102370

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