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miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity

Chronic inflammation accompanies obesity and limits subcutaneous white adipose tissue (WAT) expandability, accelerating the development of insulin resistance and type 2 diabetes mellitus. MicroRNAs (miRNAs) influence expression of many metabolic genes in fat cells, but physiological roles in WAT rem...

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Detalles Bibliográficos
Autores principales: Koh, Eun-Hee, Chernis, Natasha, Saha, Pradip K., Xiao, Liuling, Bader, David A., Zhu, Bokai, Rajapakshe, Kimal, Hamilton, Mark P., Liu, Xia, Perera, Dimuthu, Chen, Xi, York, Brian, Trauner, Michael, Coarfa, Cristian, Bajaj, Mandeep, Moore, David D., Deng, Tuo, McGuire, Sean E., Hartig, Sean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245225/
https://www.ncbi.nlm.nih.gov/pubmed/30002134
http://dx.doi.org/10.2337/db17-1378

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