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miR-30a Remodels Subcutaneous Adipose Tissue Inflammation to Improve Insulin Sensitivity in Obesity
Chronic inflammation accompanies obesity and limits subcutaneous white adipose tissue (WAT) expandability, accelerating the development of insulin resistance and type 2 diabetes mellitus. MicroRNAs (miRNAs) influence expression of many metabolic genes in fat cells, but physiological roles in WAT rem...
Autores principales: | Koh, Eun-Hee, Chernis, Natasha, Saha, Pradip K., Xiao, Liuling, Bader, David A., Zhu, Bokai, Rajapakshe, Kimal, Hamilton, Mark P., Liu, Xia, Perera, Dimuthu, Chen, Xi, York, Brian, Trauner, Michael, Coarfa, Cristian, Bajaj, Mandeep, Moore, David D., Deng, Tuo, McGuire, Sean E., Hartig, Sean M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245225/ https://www.ncbi.nlm.nih.gov/pubmed/30002134 http://dx.doi.org/10.2337/db17-1378 |
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