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Effect of Chronic Hyperglycemia on Glucose Metabolism in Subjects With Normal Glucose Tolerance

Chronic hyperglycemia causes insulin resistance, but the inheritability of glucotoxicity and the underlying mechanisms are unclear. We examined the effect of 3 days of hyperglycemia on glucose disposal, enzyme activities, insulin signaling, and protein O-GlcNAcylation in skeletal muscle of individua...

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Detalles Bibliográficos
Autores principales:	Shannon, Chris, Merovci, Aurora, Xiong, Juan, Tripathy, Devjit, Lorenzo, Felipe, McClain, Donald, Abdul-Ghani, Muhammad, Norton, Luke, DeFronzo, Ralph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2018
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245228/ https://www.ncbi.nlm.nih.gov/pubmed/30213826 http://dx.doi.org/10.2337/db18-0439

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