Antifouling Metabolites from the Mangrove Plant Ceriops tagal

The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three known metabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), were isolated from the roots of the mangrove plant Ceriops tagal. Their structures and relative stereochemistry were elucidated by means o...

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Autores principales: Chen, Jun De, Feng, Dan Qin, Yang, Zhi Wei, Wang, Zhan Chang, Qiu, Yan, Lin, Yi Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245354/
https://www.ncbi.nlm.nih.gov/pubmed/18305413
http://dx.doi.org/10.3390/molecules13020212
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author Chen, Jun De
Feng, Dan Qin
Yang, Zhi Wei
Wang, Zhan Chang
Qiu, Yan
Lin, Yi Ming
author_facet Chen, Jun De
Feng, Dan Qin
Yang, Zhi Wei
Wang, Zhan Chang
Qiu, Yan
Lin, Yi Ming
author_sort Chen, Jun De
collection PubMed
description The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three known metabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), were isolated from the roots of the mangrove plant Ceriops tagal. Their structures and relative stereochemistry were elucidated by means of extensive NMR, IR and MS analysis. Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvae of the barnacle Balanus albicostatus Pilsbry, with EC(50) values of 0.32 ± 0.01, 0.04 ± 0.00, 4.05 ± 0.15 and 18.47 ± 0.40 µg/cm(2), respectively, whereas their toxicities towards cyprids were very low, with LC(50) values all above 10 µg/cm(2).
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spelling pubmed-62453542018-11-26 Antifouling Metabolites from the Mangrove Plant Ceriops tagal Chen, Jun De Feng, Dan Qin Yang, Zhi Wei Wang, Zhan Chang Qiu, Yan Lin, Yi Ming Molecules Communication The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three known metabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), were isolated from the roots of the mangrove plant Ceriops tagal. Their structures and relative stereochemistry were elucidated by means of extensive NMR, IR and MS analysis. Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvae of the barnacle Balanus albicostatus Pilsbry, with EC(50) values of 0.32 ± 0.01, 0.04 ± 0.00, 4.05 ± 0.15 and 18.47 ± 0.40 µg/cm(2), respectively, whereas their toxicities towards cyprids were very low, with LC(50) values all above 10 µg/cm(2). MDPI 2008-01-31 /pmc/articles/PMC6245354/ /pubmed/18305413 http://dx.doi.org/10.3390/molecules13020212 Text en © 2008 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Communication
Chen, Jun De
Feng, Dan Qin
Yang, Zhi Wei
Wang, Zhan Chang
Qiu, Yan
Lin, Yi Ming
Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_full Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_fullStr Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_full_unstemmed Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_short Antifouling Metabolites from the Mangrove Plant Ceriops tagal
title_sort antifouling metabolites from the mangrove plant ceriops tagal
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245354/
https://www.ncbi.nlm.nih.gov/pubmed/18305413
http://dx.doi.org/10.3390/molecules13020212
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